Endocrine Abstracts

Case: Twenty seven year old male presented to Urologist with heamospermia. He wa noted to have a lump in his scrotum. No evidence of infection. Ultrasound showed bilateral testicular tumours. Previous medical history of congenital adrenal hyperplasia and hypertension. Medication include Atenolol and Prednisolone (poor compliance). Non smoker. Very strong family h/o cancer. O/E bilateral upper pole testicular lumps 2 cm. firm, irregular. Tumour markers normal. All blood tests n...

A 57-year lady with a history of hypertension for which she was taking bendroflumethiazide and ramipril presented with a 1 week history of worsening frontal headache and vomiting. Twenty-four hours prior to admission she became confused, had photophobia, slurred speech and was unsteady. On examination she had a Glasgow coma score of 12, was apyrexial, normotensive, tachycardic and confused. Fundoscopy was normal. There was no neck stiffness and no cranial nerve palsies. Initia...

A 67-year male presented to his GP with polydypsia, ployuria and bone pains. Routine blood tests showed hypercalcemia (corrected calcium 2.77 mmol/l). Patient was otherwise well. He had a history of ethanol abuse, hypertension and gout.Medications: Allopurinol, ramipril simvastatin and co-dydramol. Repeat blood tests after 4 weeks show a rising calcium of 3.24 mmol/l with intact PTH 33.6 pmol/l (<6.4). He was referred to our endocrinology department ...

We present a 52-year-old lady with type 2 diabetes mellitus, referred by her GP with poor glycaemic control. Her past medical history included haemochromatosis, undifferentiated connective tissue disorder, depression, hypothyroidism, pernicious anaemia and alcohol abuse. Relevant medications were metformin 1 g bd, novorapid 28 units tds, levemir 30 mg od and prednisolone 5 mg od. Her HbA1c was 8.1%, renal function and baseline pituitary function was normal. Following an admiss...

Prolonged use of oral corticosteroid treatment is associated with cushingoid side effects and HPA suppression. We are increasingly seeing similar problems associated with nasal steroid therapy.Case 1: A 41-year-old lady with history of asthma, allergic rhinitis and nasal polyps presented with a clinical appearance of Cushings syndrome. Her medication included Becloforte inhalers 250 mg tds and Betamethasone sodium phosphate nasal drops 0.1% 2 drops bd, b...